Mudd, Joseph

Joseph Mudd's lab iseeks to understand the underlying mechanisms of differential disease outcomes in progressive and non-progressive SIV infection. In the former setting, a major aspect of the work is interested in examining the immunological and virological factors favoring viral persistence in the GI tract during ART. In the latter setting, Mudd examines the molecular mechanisms governing HIV entry receptor control, a host adaptation that has evolved to allow natural hosts to subvert disease progression.